Lotte is direct and edgy, amiable and, above all, equipped with a big-city snout. With all these qualities, she is constantly offending her colleagues, friends and even her boyfriend. He throws her out without further ado and Lotte finds herself out on the street - from now on fully occupied with finding a place to stay. Then she meets Marcel, an almost forgotten acquaintance, in her local pub at night. As soon as he recognizes her, Lotte flees and finds a place to stay in her friend Sabine's apartment. The next day, the stresses and strains of that night haunt Lotte and don't seem to let her go, even during her work at the hospital. But then a young girl at the hospital seeks out the headstrong woman. But what connection does Greta have to Lotte's friend Marcel? Lotte quickly realizes that meeting Greta will not allow her to escape this time.